Prerequisite: STAT 656, STAT 652, working knowledge of statistical programming language.
Course Description: Advanced statistical methods in the drug development process. Provides the theoretical statistical basis for the design and analysis of pharmaceutical clinical trials. Topics include the theory of randomization, randomization-based inference, restricted, response-adaptive, and covariate-adaptive randomization, the modern theory of group sequential monitoring, statistical aspects of determination of dose-response relationships.
When Offered: Offered on an irregular basis.